Losartan potassium generic name

Losartan potassium generic name DEFAULT

Cozaar vs generic Cozaar (losartan potassium)

If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.

Losartan potassium is the generic name for the prescription medication sold under the brand name Cozaar. This medication is also available as a generic drug, which is sometimes called &#;generic Cozaar.&#; The FDA requires that companies that want to produce generic drugs prove that they&#;re the same as the brand-name medication. 

These generic drugs have to have the same efficacy and safety of the original brand-name prescription medication and be offered in the same strength, dosage form, and route of administration (FDA, ).

  • Losartan potassium is the generic name for the drug sold under the brand name Cozaar, and it is sometimes called &#;generic Cozaar.&#;
  • The U.S. Food and Drug Administration requires that makers of generic drugs prove they&#;re just as effective as the brand-name version.
  • Generic Cozaar is just as safe and effective as brand-name Cozaar and comes in the same strength and dosages.
  • Some lots of generic losartan have been recalled for containing too much of a certain compound.
  • Speak with a medical professional before discontinuing your medication abruptly, as this can cause serious adverse effects.

Generic Cozaar belongs to a class of drugs called angiotensin receptor blockers (ARBs) that also includes the medications valsartan and irbesartan. ARBs are generally used to treat high blood pressure, but they have other &#;off-label&#; uses. Losartan is approved by the U.S. Food and Drug Administration (FDA) to treat high blood pressure (hypertension), risk of stroke, and kidney problems from diabetes (diabetic nephropathy). 

However, it may not be as effective at reducing stroke risk in Black people with high blood pressure and left ventricular hypertrophy (enlarged heart) than it is in other groups of people (DailyMed, ).

Generic Cozaar may also be used off-label after a heart attack to help individuals with heart failure who cannot tolerate ACE inhibitors and treat non-diabetic kidney disease. It may also be used to help prevent a life-threatening complication that&#;s common in people who have Marfan&#;s syndrome, an inherited connective tissue disorder (UpToDate, n.d.). 

Losartan potassium is not an ACE inhibitor. Although ARBs and ACE inhibitors are related and act on the same system in order to lower blood pressure, they interfere with different parts of the system. Angiotensin II is a hormone that causes blood vessels to constrict. 

Too much angiotensin may lead to high blood pressure over time. ARBs block the actions of angiotensin II, whereas ACE inhibitors block an enzyme that makes angiotensin (Burnier, ; Sweitzer, ). These prescription drugs prevent this squeezing, just in different ways, in order to lower blood pressure (DailyMed, ).

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Certain lots of generic medications containing losartan were recalled by Torrent Pharmaceuticals Limited in This company makes generic Cozaar, not the brand-name medication, which is produced by Merck. The recall does not include all lots of these medications produced (FDA, ).

These medications were recalled for containing too much of a compound called N-Methylnitrosobutyric acid (NMBA). The FDA allows certain amounts of NMBA in products, but some lots of these medications have passed the cutoff for what is considered an acceptable daily intake (FDA, ).

You should contact your pharmacist or healthcare provider for instructions before discontinuing your medication, even if your lot of generic Cozaar was affected. It can be more dangerous to abruptly stop taking your medication than to continue to take losartan products affected by this recall. Your pharmacist may be able to offer an alternative treatment that allows you to stop taking losartan without risking adverse effects (FDA, ).

The standard starting dose for adults taking losartan is 50mg, taken once a day in the form of a tablet. The suggested starting dose for each of this medication&#;s FDA-approved uses is the same. Those being treated for high blood pressure with left ventricular atrophy may be prescribed losartan and a diuretic such as hydrochlorothiazide as an adjunct treatment (FDA, ).

Some individuals with specific health considerations may be started on a lower dose of losartan (25mg), taken once daily. Those with liver problems or possible volume depletion, a condition caused by the loss of blood sodium that may happen when a patient is also prescribed diuretics (also called &#;water pills&#;), will likely be placed on this lower dose to begin (FDA, ).

For some people, 50mg of losartan may not be enough to adequately lower high blood pressure. These individuals may have their dosage increased from 50mg to mg, taken once daily (FDA, ).

The most common possible side effects of losartan include upper respiratory infection, dizziness or lightheadedness, stuffy nose, back pain, chest pain, diarrhea, high levels of potassium, low blood pressure, low blood sugar, and tiredness (FDA, ). 

Generic Cozaar may cause a severe allergic reaction—including hives, itching, rash, and trouble breathing. Other serious side effects include low blood pressure (hypotension), changes in kidney function that may include kidney failure in some cases, and high blood potassium (hyperkalemia) (UpToDate, n.d.). Hyperkalemia can be mild or serious, potentially causing heart problems such as arrhythmias (irregular heartbeat), muscle weakness, or paralysis (Simon, ). 

Since high blood levels of potassium can be dangerous, you may need to avoid high-potassium foods when taking ARBs such as generic Cozaar. Past research suggests that high dietary potassium may be safe for people with proper kidney function since the kidneys get rid of any excess (Malta, ; National Kidney Foundation, ). 

But that also means those taking ARBs such as losartan who already have kidney problems such as chronic kidney disease (CKD) may need to limit high-potassium foods such as potatoes, tomatoes, oranges, and bananas (Han, ). 

Salt substitutes that use potassium chloride and potassium supplements should also be avoided by anyone taking generic Cozaar. These sources of potassium have not been proven safe like dietary potassium and should be avoided even if you have normal kidney function. Your serum potassium levels may be used to determine how much high-potassium foods should be limited. 

Losartan may also cause serious adverse effects when combined with certain medications. Toxicity may result from combining losartan and lithium. Taking non-steroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen and naproxen) while on losartan may weaken this antihypertensive drug&#;s effect. Drug interactions such as dangerously low blood pressure may also occur if this prescription medicine is mixed with ACE inhibitors and aliskiren, a different type of medication that&#;s also used to lower blood pressure (DailyMed, ). 

Certain people should not take losartan or use this medication with caution. Since the liver breaks down this prescription medication, people with abnormal liver function may develop losartan levels in their system that are too high. Lower doses of the medication may be needed for these individuals. Those with renal artery stenosis, narrowing of the artery to the kidney, may worsen kidney function by taking losartan (DailyMed, ).

You should stop taking losartan if you become pregnant as the drug may cause fetal death or injury if taken during the final six months (second and third trimester) of pregnancy. You should not breastfeed when taking losartan as the medication may pass into the breast milk (FDA, ). 

Tell your healthcare provider or pharmacist about what other drugs or over-the-counter supplements you&#;re taking before starting so they can advise on your specific case.

  1. Burnier, M. (). Angiotensin II Type 1 Receptor Blockers. Circulation, (6), doi/cir Retrieved from https://www.ahajournals.org/doi//cir
  2. DailyMed &#; Losartan Potassium tablets 25 mg, film coated (). Retrieved on 2 September from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a3fa4-c65b-4ff2e-fef80cb84
  3. Food and Drug Administration (FDA). (, June 01). Generic Drug Facts. Retrieved August 09, , from https://www.fda.gov/drugs/generic-drugs/generic-drug-facts
  4. Food and Drug Administration (FDA). (, April 18). Updated: Torrent Pharmaceuticals Limited Expands Voluntary Nationwide Recall of Losartan Potassium Tablets, USP and Losartan Potassium/Hydrochlorothiazide Tablets, USP. Retrieved September 09, , from https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/updated-torrent-pharmaceuticals-limited-expands-voluntary-nationwide-recall-losartan-potassium
  5. Han, H. (). Blood pressure medications: ACE-I/ARB and chronic kidney disease. Journal of Renal Nutrition, 23, e–e Retrieved from https://www.jrnjournal.org/article/S%%/pdf
  6. Malta, D., Arcand, J., Ravindran, A., Floras, V., Allard, J. P., & Newton, G. E. (). Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. The American Journal of Clinical Nutrition, (4), doi/ajcn Retrieved from https://academic.oup.com/ajcn/article//4//
  7. National Kidney Foundation. (, August 26). What is Hyperkalemia? Retrieved September 02, , from https://www.kidney.org/atoz/content/what-hyperkalemia
  8. Simon, L. V., Hashmi, M. F., & Farrell, M. W. (). Hyperkalemia. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK/
  9. Sweitzer, N. K. (). What Is an Angiotensin Converting Enzyme Inhibitor? Circulation, (3), EE doi/cir Retrieved from https://www.ahajournals.org/doi/full//cir
  10. UpToDate &#; Losartan: Drug Information (n.d.). Retrieved on 24 August from https://www.uptodate.com/contents/losartan-drug-information?search=losartan&source=panel_search_result&selectedTitle=1~69&usage_type=panel&kp_tab=drug_general&display_rank=1#F
Sours: https://www.getroman.com/health-guide/cozaar-vs-generic-cozaar/

Losartan potassium: Uses and warnings

Losartan potassium is a medication that doctors prescribe to treat high blood pressure or hypertension.

Losartan potassium works by relaxing the blood vessels to allow the blood to flow more efficiently, which reduces a person’s blood pressure. The United States Food and Drug Administration (FDA) in to treat hypertension.

The World Health Organization (WHO) include losartan potassium on their , which catalogs the most effective and safe medications that experts consider necessary in a healthcare system.

People should not use this medication while pregnant.

This article provides an overview of losartan potassium, including its uses, side effects, potential drug interactions, and other warnings.

What is losartan potassium used for?

Losartan potassium is a type of angiotensin receptor blocker (ARB) known by the brand name Cozaar. Doctors prescribe it to treat hypertension and nephropathy, which is damage to the kidneys, in people with type 2 diabetes.

Doctors most commonly prescribe losartan potassium to treat hypertension in adults and children over 6 years of age.

For many people, lifestyle changes, such as diet, exercise, and avoiding smoking and alcohol, are sufficient to reduce blood pressure to healthy levels. Others may need medication to control their blood pressure.

Untreated high blood pressure can have serious health consequences. Reducing high blood pressure protects against some related health conditions, including:

Medications such as losartan potassium are just one aspect of hypertension treatment. Others include lifestyle and dietary changes. Sometimes, individuals will take losartan alongside other medicines, including diuretics, to control their high blood pressure.

People with diabetes may take losartan to protect their kidneys from damage that occurs as the result of the disease, such as diabetic nephropathy.

How effective is losartan potassium?

The WHO consider losartan as safe, effective, and necessary in a health system. Many research studies also report that the medication is both safe and effective for a variety of uses.

A , which reviewed the previous 15 years of losartan use, reports that the drug is beneficial for:

  • controlling hypertension
  • decreasing stroke risk
  • reducing proteinuria, which is an abnormal amount of protein in the urine that suggests kidney damage
  • slowing diabetic nephropathy

The research also states that losartan potassium has other positive effects, including:

  • decreased uric acid levels: uric acid contributes to the development of gout
  • reduced platelet aggregation: platelet aggregation increases blood clot risk
  • regression of left ventricular hypertrophy: enlargement of the heart’s left ventricle, which raises the risk of heart problems

Losartan potassium can cause dizziness, but it produces few other side effects. A study suggests that losartan has a lower incidence of side effects yet is just as effective as other drugs for hypertension.

This medication is also effective in young people. A looked at the effects of losartan potassium in children and adolescents, with a median age of 12, whose hypertension had not improved through lifestyle changes. They found that the treatment reduced blood pressure more than a placebo.

Side effects

Dizziness is a common side effect of losartan. This usually affects people who are just beginning treatment, as their bodies are adjusting to the drug.

Other side effects include:

  • upper respiratory infection
  • nasal congestion
  • back pain

To prevent dizziness or associated injuries, doctors advise people to change positions slowly. For example, carefully move from a lying position to a sitting one, and from a seated position to an upright one.

Avoid driving or using heavy machinery while dizzy. See a doctor if dizziness or lightheadedness persists or gets worse.

Most people do not experience serious adverse reactions to losartan potassium.

If serious side effects do occur, seek urgent medical attention. These include:

  • chest pain
  • fainting
  • irregular heartbeat or palpitations
  • muscle weakness
  • unusual changes in the amount of urine output
  • vomiting

Call or go to the nearest emergency department if symptoms of an allergic reaction to the drug occur. Allergy symptoms include:

  • breathing difficulties
  • itching
  • loss of consciousness
  • rash
  • severe dizziness
  • swelling of the face, tongue, or throat

Allergic reactions to losartan are rare.

Losartan potassium warnings

Losartan potassium is not suitable for everyone. People with hypertension should consider and talk to a doctor about the following factors before taking losartan potassium:

Drug allergies

People who are allergic to losartan potassium or other inactive ingredients in the drug should avoid it. Inactive ingredients in Cozaar are:

  • hydroxypropyl cellulose
  • hypromellose
  • anhydrous lactose
  • magnesium stearate
  • microcrystalline cellulose
  • cornstarch
  • titanium dioxide

Inform a doctor or pharmacist of all drug allergies before taking losartan.

Pregnancy, trying to conceive, or breast-feeding

Losartan and similar medicines can affect a fetus. They may affect the kidney function of the fetus and increase their risk of illness or death.

People taking losartan should speak to their doctor immediately after confirming the pregnancy, as they will likely need to stop taking the medication until the baby is born.

The FDA advise that people who breast-feed should not take losartan, as they do not know whether or not the medication passes into the breast milk.

Medical conditions or symptoms

People who have any of the following conditions should speak to their doctor before taking losartan:

Drug interactions

Losartan potassium can interact with some drugs and supplements. People should give their doctor a complete list of the prescription medications, non-prescription medications, vitamins, and supplements they take.

Among others, losartan may interact with:

How to take losartan potassium and dosage

Losartan potassium, sold as Cozaar, is available in tablet form in three doses:

  • 25 milligrams (mg)
  • 50 mg
  • mg

The dosage of losartan a person will take will depend on several factors. Their doctor will prescribe the necessary dose for their age, weight, condition, and overall health.

General guidelines for losartan potassium dosage are as follows:

  • Hypertension. Typically, people will take 50 mg once a day, although some individuals may require mg daily. A doctor may prescribe other hypertension drugs or diuretics in addition to losartan.
  • Nephropathy in people with type 2 diabetes. People with diabetes typically begin on 50 mg daily, which may increase to mg daily depending on their reaction to the drug.
  • Hypertension in people with left ventricular hypertrophy. The starting dose is usually 50 mg, and this may increase to mg daily.
  • Hypertension in children. Children aged 6 and over may begin on a very low dose. Rarely, they may require up to 50 mg of losartan per day, depending on their blood pressure response.

Always take losartan exactly as a doctor prescribes. Swallow the tablet with a glass of water, with or without food. Take missed doses as soon as possible, but do not take 2 doses close together. Only take one dose at a time.

A losartan overdose that causes severe symptoms requires emergency medical attention. Call right away. For less severe symptoms, call the American Association of Poison Control Centers at

Summary

Losartan potassium is a hypertension treatment. Research suggests that the medication is safe and effective for most people. People may experience mild side effects, such as dizziness, in the early stages of treatment.

People who experience severe or persistent side effects should contact their doctor right away. Seek emergency medical attention for symptoms that affect breathing or cause swelling of the mouth or throat.

To reduce blood pressure and avoid complications, always take losartan according to a doctor’s instructions. Be sure to discuss any concerns about losartan or its effects with a medical professional.

Sours: https://www.medicalnewstoday.com/articles/
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Losartan, oral tablet

Highlights for losartan

  1. Losartan oral tablet is available as a brand-name drug and a generic drug. Brand name: Cozaar.
  2. Losartan comes only as a tablet you take by mouth.
  3. Losartan is used to treat hypertension (high blood pressure) in adults and some children. It’s also used to help your kidneys work better if you have diabetes. In addition, it’s used to reduce your risk of stroke if you have high blood pressure and a heart condition called left ventricular hypertrophy.

What is losartan?

Losartan is a prescription drug. It comes as an oral tablet.

Losartan is available as the brand-name drug Cozaar. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Losartan may be taken as part of a combination therapy with other medications to lower your blood pressure.

What’s losartan used for?

Losartan is used for three main purposes. It’s used to:

  • treat high blood pressure in adults and some children
  • lower the risk of stroke in adults with high blood pressure and left ventricular hypertrophy (LVH), which is a condition that causes the walls in the heart’s left ventricle to thicken
  • treat diabetic nephropathy, which is kidney disease caused by diabetes, in certain adults with type 2 diabetes and high blood pressure, either currently or in the past

Losartan drug class

Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). A class of drugs is a group of medications that work in a similar way. They’re often used to treat similar conditions.

Other ARBs include olmesartan, valsartan, and telmisartan. Like losartan, these drugs can be used to treat high blood pressure and other heart problems.

How losartan works

Losartan works by blocking the action of angiotensin II, a chemical in your body that causes your blood vessels to tighten and narrow. Losartan helps relax and widen your blood vessels. This lowers your blood pressure.

This action helps treat high blood pressure as well as the other two conditions losartan is usually prescribed for. High blood pressure and left ventricular hypertrophy (LVH) increase your risk of stroke, so lower blood pressure reduces your risk.

Lower blood pressure also reduces your risk of kidney damage. This is because high blood pressure raises your risk of kidney damage that’s caused by the high blood sugar levels linked with diabetes.

Losartan side effects

Losartan can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking losartan. This list does not include all possible side effects.

For more information on the possible side effects of losartan, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.

More common side effects

The more common side effects that can occur with losartan include:

  • upper respiratory infections, such as the common cold
  • dizziness
  • stuffy nose
  • back pain
  • diarrhea
  • fatigue
  • low blood sugar
  • chest pain
  • high or low blood pressure

These effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • High potassium blood levels. Symptoms can include:
    • heart rhythm problems
    • muscle weakness
    • slow heart rate
  • Allergic reactions. Symptoms can include:
    • swelling of your face, lips, throat, or tongue
  • Low blood pressure. Symptoms can include:
  • Kidney disease. Symptoms can include:
    • swelling in your feet, ankles, or hands
  • Unexplained weight gain

Losartan may interact with other medications

Losartan can interact with several other medications. Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

Below is a list of medications that can interact with losartan. This list does not contain all drugs that may interact with losartan.

Before taking losartan, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Lithium

Taking losartan with lithium, a drug used to treat bipolar disorder, may increase the levels of lithium in your body. This can increase your risk of dangerous side effects.

If you need to take these drugs together, your doctor may reduce your lithium dosage.

Blood pressure drugs

Taking losartan with other drugs that work in the same way may increase your chance of low blood pressure, high potassium levels in your blood, and kidney damage.

Examples of these drugs include:

  • angiotensin receptor blockers (ARBs), such as:
    • irbesartan
    • candesartan
    • valsartan
  • angiotensin-converting enzyme (ACE) inhibitors, such as:
    • lisinopril
    • fosinopril
    • enalapril
    • aliskiren

Nonsteroidal anti-inflammatory drugs (NSAIDs)

You shouldn’t take NSAIDs with losartan. Using losartan with NSAIDs raises your risk of kidney damage. Your risk may be higher if:

  • you have poor kidney function
  • are a senior
  • take a water pill
  • are dehydrated

NSAIDs may also reduce the blood-pressure-lowering effects of losartan. This means that losartan may not work as well if you take it with an NSAID.

Examples of NSAIDs include:

Rifampin

Taking losartan with rifampin, a drug used to treat tuberculosis, can increase how quickly your body removes losartan. This means that losartan may not work as well to lower your blood pressure if you take it with these drugs.

Diuretics (water pills)

Losartan can cause low blood pressure. Your risk of low blood pressure is increased if you also take diuretics. Symptoms of low blood pressure can include dizziness or feeling faint, or chest pain. Examples of diuretics include:

  • hydrochlorothiazide
  • furosemide
  • spironolactone

Drugs or supplements that contain potassium

Losartan can increase the levels of a substance called potassium in your blood. Taking losartan with drugs that contain potassium, potassium supplements, or salt substitutes with potassium, can increase your risk of hyperkalemia (high levels of potassium).

Examples of drugs that contain potassium include:

  • potassium chloride (Klor-Con, Klor Con M, K-Tab, Micro-K)
  • potassium gluconate
  • potassium bicarbonate (Klor-Con EF)

How to take losartan

The losartan dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using losartan to treat
  • your age
  • your weight
  • other medical conditions you may have, such as liver damage

Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Drug forms and strengths

Generic: Losartan

  • Form: oral tablet
  • Strengths: 25 milligrams (mg), 50 mg, mg

Brand: Cozaar

  • Form: oral tablet
  • Strengths: mg

Dosage for high blood pressure (hypertension)

Adult dosage (ages 18–64 years)

The typical starting dosage is 50 mg once daily. Dosages range between 25 and mg per day. You take losartan once or twice per day.

Child dosage (ages 6–17 years)

The dosage is based on your child’s weight. The usual dosage is around mg/kg of body weight taken once per day. Your child’s doctor will increase or decrease the dosage depending on your child’s response to the medication.

Child dosage (ages 0–5 years)

This drug should not be used in children younger than 6 years.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosage. Seniors may process drugs more slowly. As a result, a normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage, or a different dosing schedule.

Dosage for diabetic nephropathy

Adult dosage (ages 18–64 years)

The typical starting dosage is 50 mg once daily. Your doctor may increase your dosage to mg per day if needed. You take losartan once or twice per day.

Child dosage (ages 0–17 years)

This drug should not be used in children younger than 17 years for this condition.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosage. Seniors may process drugs more slowly. As a result, a normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage, or a different dosing schedule.

Dosage to reduce stroke risk in people with high blood pressure and left ventricular hypertrophy

Adult dosage (ages 18–64 years)

The typical dosage is 50 mg taken once daily. Your doctor may increase your dosage to mg per day if needed. You may take losartan once or twice per day.

Child dosage (ages 0–17 years)

This drug should not be used in children younger than 17 years for this condition.

Senior dosage (ages 65 years and older)

There are no specific recommendations for senior dosage. Seniors may process drugs more slowly. As a result, a normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage, or a different dosing schedule.

Special dosage considerations

For people with liver problems: If you have mild-to-moderate liver problems, your doctor may lower your starting dosage to 25 mg per day.

Warnings

Allergy warning

Losartan can cause a severe allergic reaction. Symptoms include:

  • trouble breathing
  • swelling of your throat or tongue
  • hives

If you develop these symptoms, call or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Alcohol interaction warning

Consuming alcoholic drinks while taking losartan can cause a sedative effect. This means you may have slowed reflexes, poor judgment, and sleepiness. This effect can be dangerous if you drive or use other machinery.

Alcohol can also increase the blood pressure-lowering effect of losartan. This increases the risk of your blood pressure getting too low.

Low blood pressure warning

This drug may cause low blood pressure, which can make you feel faint or dizzy. If this happens, lie down and call your doctor right away.

Warnings for people with certain health conditions

For people with kidney problems: This medication can make kidney disease worse. Symptoms of worsening kidney disease include:

  • swelling in your hands, feet, or ankles
  • unexplained weight gain

For people with liver problems: If you have liver problems, your body won’t break down losartan as effectively as normal. For this reason, your doctor may lower your starting dosage.

For people with diabetes and taking aliskiren: You should not take losartan if you have diabetes and are take a drug called aliskiren to reduce blood pressure. Taking both of these drugs can increase your risk of side effects from losartan. Side effects include low blood pressure, high potassium levels in your blood, and kidney damage. If you have diabetes and are taking aliskiren, talk with your doctor before starting losartan.

Warnings for other groups

For pregnant women: Losartan is a category D pregnancy drug. That means two things:

  1. Studies show a risk of adverse effects to the fetus when the mother takes the drug.
  2. The benefits of taking the drug during pregnancy may outweigh the potential risks in certain cases.

This drug can harm or end your pregnancy. Tell your doctor if you’re pregnant or plan to become pregnant. Losartan should be used during pregnancy only if the potential benefit justifies the potential risk.

For women who are breastfeeding: It isn’t known if losartan passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk with your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: Seniors may process drugs more slowly. As a result, a normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage, or a different dosing schedule.

For children: This medication should not be used in children younger than 6 years with high blood pressure.

For Black people: Losartan may not work as well in Black people with certain health problems. For more information, talk with your doctor.

Take as directed

Losartan is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you don’t take it at all: Losartan lowers high blood pressure. If you don’t take it, your blood pressure will stay high. High blood pressure increases your risk of a stroke or heart attack.

If you don’t take it on schedule: Your blood pressure may not improve or may get worse. You may increase your risk of a heart attack or stroke.

What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. If it’s just a few hours until the time for your next dose, wait and only take one dose at that time. Never try to catch up by taking two doses at once. This could cause dangerous side effects.

If you take too much: If you take too much losartan, you may have symptoms such as:

  • feeling like your heart is pounding
  • weakness
  • dizziness

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at or through their online tool. But if your symptoms are severe, call or go to the nearest emergency room right away.

How to tell if the drug is working: Your blood pressure should be lower. Your doctor will monitor your blood pressure at your checkups. You can also check your blood pressure at home.

You may not be able to tell if this drug is helping your kidney function or reducing your risk of stroke. That doesn’t mean that the drug isn’t working. Keep taking this drug unless your doctor tells you to stop.

Important considerations for taking losartan

Keep these considerations in mind if your doctor prescribes losartan for you.

General

You can cut or crush losartan tablets.

Storage

  • Store losartan at room temperature between 59°F and 86°F (15°C and 30°C).
  • Don’t freeze this drug.
  • Keep this medication away from light.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport X-ray machines. They can’t harm your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

You may need to check your blood pressure at home. To do this, you may need to buy a home blood pressure monitor. You should keep a log with the date, the time of day, and your blood pressure readings. Bring this log with you to your doctor appointments.

Shop for blood pressure monitors.

Clinical monitoring

During treatment with losartan, your doctor may check your:

  • potassium levels
  • kidney function
  • blood pressure

Hidden costs

You may need to buy a blood pressure monitor to check your blood pressure at home. These monitors are available at most pharmacies.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk with your doctor about other options that may work for you.

Disclaimer:Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Sours: https://www.medicalnewstoday.com/articles/losartan-oral-tablet
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